Back to Job Search

Research Scientist, Computational Protein Design - Full-time

  • Location: Cambridge
  • Salary: US$80000.00 - US$120000.00 per annum per year
  • Job Type:Permanent

Posted 16 days ago

  • Sector: Life Sciences
  • Contact: Amber Mitchell
  • Expiry Date: 21 August 2022
  • Job Ref: JN -072022-472336

We are looking for a highly experienced Research Scientist to join a next-generation industrial biotechnology company headquartered in Cambridge, Massachusetts. The chosen individual will specialize in computational protein design. This candidate should have deep experience in protein modeling or design as well as growing skills in machine-learning/deep learning. This is a full-time opportunity and direct hire opportunity, that will report directly to their Cambridge, MA facility.


  • Develop predictive models for enzyme engineering using machine-learning/deep-learning techniques
  • Leverage the in-house enzyme engineering data to enhance machine-learning/deep-learning models
  • Develop and implement computational approaches using 3D structures and/or sequences as input to increase enzyme stability, solubility and activity

Required qualifications:

  • Ph.D. in Bioengineering, Biochemistry, Chemical Engineering, Computer Science, or similar discipline
  • Experience with protein modeling or design using Rosetta

Preferred qualifications:

  • Experience with one or more additional protein modeling and design software packages such as Schrodinger, Discovery Studio, MOE, GROMACS, Amber, or NAMD
  • Experience using computational tools to improve enzyme activity and specificity

Please apply with your most up to date resume to be considered.