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Formulation Scientist

  • Location: San Diego
  • Salary: Negotiable per hour
  • Job Type:Contract

Posted 19 days ago

  • Sector: Life Sciences
  • Contact: Taylor Cochran
  • Duration: 6 months
  • Start Date: 07/25/2022
  • Expiry Date: 18 August 2022
  • Job Ref: JN -062022-471362

Currenlty in search of a Formulation Scientist to join a leading Pharmaceutical company based in San Diego, CA. The candidate will be responsible for exploring the formulation space for supporting a variety of preclinical studies to advance molecules to the clinic. The candidate is expected to help lay the foundations for future clinical development by successfully executing developability assessments and robust experimental physicochemical characterization of molecules and prediction of in-vivo bioperformance using modeling tools. The candidate will collaborate extensively with colleagues in discovery biology, chemistry, DMPK, and CMC functions.

The successful candidate will possess:

  • Sound knowledge of pharmaceutical principles in the preformulation development with a range of dosage forms, including solution, suspension and IV formulations to support PK, pharmacology, and toxicology studies
  • Hands-on experience in analytical techniques such as HPLC methods, PXRD, TGA, DSC, and particle size analyses to enable evaluation of early-stage discovery compounds
  • Hans on experience in cell culture and in vitro permeability assay using Caco-2 cells
  • Excellent verbal and written communication skills
  • Successful and efficient multitasking and working as part of a multidisciplinary team that works within defined timelines

Minimum Qualifications

· Ph.D. (or equivalent degree) in chemistry or pharmaceutical sciences and 0-3 years of productive, relevant industrial and or post-doctoral work experience, or M.S. (or equivalent degree) with 3+ years of productive, relevant industry work experience

Preferred Qualifications:

· Experience in laboratory techniques commonly used in the analysis of preformulation such as HPLC, PXRD, TGA, and DSC is required

· Experience in the LC/MS/MS

· Mammalian cell culture and in vitro permeability assay

· Conducting preliminary form and salt screen. Hands-on knowledge in form and salt selection methods.