JOB TITLE:
Analytical Chemistry Scientist II
LOCATION:
San Diego, CA – Onsite
SCHEDULE:
8:00 AM – 5:00 PM
DURATION:
12-month contract
PAY:
40-45 USD per hour
Job Responsibilities:
In this role, you will support analytical method development, validation, and transfer within a fast-paced biopharmaceutical environment focused on oligonucleotide synthesis and testing. Key responsibilities include:
- Developing, optimizing, validating, and transferring analytical methods for oligonucleotides, raw materials, and reagent consumables
- Designing, planning, and executing laboratory experiments with minimal supervision
- Managing multiple assignments and delivering high-quality results within project timelines
- Performing data analysis, interpreting results, and troubleshooting analytical issues
- Preparing study protocols, technical reports, and assay work instructions with high attention to detail
- Ensuring compliance with GMP, Good Documentation Practices (GDP), and internal quality standards
- Supporting cross-functional collaboration and continuous improvement initiatives
- Performing additional duties as assigned by management
Essential Duties and Job Functions:
- Execute and support analytical method development, qualification, validation, and transfer activities
- Perform hands-on laboratory work using chromatographic and spectroscopic techniques
- Conduct oligonucleotide characterization and release testing
- Ensure accurate documentation and adherence to regulated laboratory practices
- Investigate and resolve unexpected analytical results using scientific problem-solving approaches
- Collaborate with cross-functional teams to support method lifecycle activities
- Contribute to assay development, optimization, and standardization efforts
- Maintain compliance with FDA cGMP, ICH guidelines, USP requirements, and internal quality systems
- Support continuous improvement initiatives within analytical development workflows
Knowledge & Skills:
- Strong hands-on laboratory skills with excellent organization and documentation practices
- Proficiency in analytical techniques including HPLC, LC-MS, UV-Vis, FTIR, Karl Fischer, and NMR
- Experience with oligonucleotide analysis and characterization
- Strong understanding of method development, validation principles, and regulatory expectations (FDA, ICH, USP)
- Excellent problem-solving, analytical thinking, and troubleshooting abilities
- Ability to manage multiple priorities in a fast-paced, deadline-driven environment
- Strong communication skills (verbal and written) and ability to collaborate across teams
- Familiarity with GMP environments and quality systems
- High attention to detail and commitment to data integrity
- Ability to work independently while contributing effectively in a team setting
Education & Experience:
- Bachelor’s, Master’s, or Ph.D. in Analytical Chemistry, Chemistry, Biochemistry, Molecular Biology, or related scientific field
- Minimum 2 years of hands-on experience in analytical method development, validation, qualification, and transfer
- Direct experience with oligonucleotide analytical testing strongly preferred
- Experience working in GMP-regulated or pharmaceutical/biotech environments preferred
- Strong academic or industry background in chromatographic and spectroscopic methods required
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